Israeli forces have battled Hamas-led fighters in several parts of the Gaza Strip, and Palestinian health officials say at least 50 people were killed in Israeli bombardments of southern and central areas.
The Palestinian Islamist militant group Hamas has accused Israel of stepping up attacks in Gaza to try to derail efforts by Arab mediators and the United States to reach a ceasefire deal.
Israel says it is trying to root out Hamas fighters.
In Rafah, a southern border city where Israeli forces have been operating since May, five Palestinians were killed in an air strike on a house, the Gaza health officials said.
In nearby Khan Younis, a man, his wife, and two children were killed, they said.
Later on Tuesday, an Israeli air strike on a car killed at least 17 Palestinians and wounded 26 others in Khan Younis in southern Gaza on Tuesday, the officials said.
The air strike hit near a tented area housing displaced families in Attar Street, the health ministry said.
In the historical Nuseirat camp in central Gaza, at least four Palestinians were killed in separate shelling and aerial strikes in central Gaza, medics said.
An Israeli air strike killed four in Sheikh Zayed in northern Gaza, they said.
Hours later, an Israeli air strike on a school in the Nuseirat camp killed 16 people and wounded many others, health officials said.
The strike hit a UN-run school, which housed displaced families, the ministry said.
The Israeli military said troops continued "intelligence-based" activities in Rafah, and that air strikes had targeted militants, tunnels, and other Hamas military infrastructure.
It said the Israeli air force had struck about 40 targets across the enclave, including sniping and observation posts, military structures, and buildings rigged with explosives.
The armed wings of Hamas and Islamic Jihad, a Hamas ally, said their fighters had attacked Israeli forces in several locations with anti-tank rockets and mortar bombs.
Islamic Jihad's armed wing said it had fired missiles at Sderot in southern Israel. There was no word of any deaths or serious damage.
Israel vowed to eradicate Hamas after its militants killed 1200 people and took more than 250 hostage in an attack on southern Israeli communities last October 7, according to Israeli tallies.
At least 38,713 Palestinians have been killed in Israel's retaliatory offensive since then, Gaza health authorities said in their latest update on Tuesday.
Israel also says 326 of its soldiers have been killed in Gaza.
Relatives visited Al-Aqsa Hospital in Deir Al-Balah in central Gaza to say farewell to relatives before funerals.
Efforts mediated by Egypt and Qatar to end the conflict and release the hostages, as well as Palestinians in Israeli jails, had appeared to be making some progress, negotiators had said.
The talks stalled on Saturday after three days of intense negotiations failed to produce a viable outcome, Egyptian security sources said, and after an Israeli strike targeting Hamas' top military chief, Mohammed Deif.
The attack in the Khan Younis area killed more than 90 people and wounded hundreds, Gaza health authorities said.
A Palestinian official close to the negotiations told Reuters Hamas was keen not to be seen as halting the talks despite the stepped-up Israeli attacks.
"Hamas wants the war to end, not at any price. It says it has shown the flexibility needed and is pushing the mediators to get Israel to reciprocate," the official said.
He said Hamas believed Israeli Prime Minister Benjamin Netanyahu was trying to avoid a deal by adding more conditions that restrict the return of displaced people to northern Gaza and to maintain control over the Rafah border crossing with Egypt.
US State Department spokesperson Matthew Miller said on Monday that two senior advisers to Netanyahu had said Israel was still committed to reaching a ceasefire.
