Essendon will welcome back key trio Darcy Parish, Mason Redman and Jake Kelly as they attempt to bounce back to winning ways against an in-form but undermanned St Kilda.
Gun Carlton defender Jacob Weitering returns for their Good Friday clash with North Melbourne, while Melbourne have named sore stars Jake Lever and Clayton Oliver to face Port Adelaide.
Parish and Kelly have been named to return from hamstring tightness and illness respectively, while Redman has completed his one-game striking suspension.
It is Parish's first game this season after a pre-season hamstring injury.
The Bombers haven't directly replaced suspended spearhead Peter Wright, while former first-round pick Elijah Tsatas and fellow youngster Alwyn Davey Jnr have been dropped.
The Saints have had to make three forced changes.
Key forward Anthony Caminiti will replace Max King (suspension), while draftee Angus Hastie will debut and Dan Butler returns in place of injured duo Mason Wood and Liam Henry.
Carlton gun Weitering returns from a calf injury, alongside fellow defender Caleb Marchbank, who has recovered from illness, with Brodie Kemp and Lachie Young making way.
Former Sun Elijah Hollands will make his club debut after serving his two-match illicit drugs ban, replacing injured utility David Cuningham (calf).
North Melbourne have named an unchanged team.
The Demons made just one change for Saturday night's blockbuster at Adelaide Oval, with midfielder Taj Woewodin coming in for Steven May, who is recovering from broken ribs.
Lever suffered a minor knee injury in last week's win over Hawthorn while Oliver dislocated his finger at Thursday's training.
The Demons have opted against a like-for-like replacement for sidelined defensive rock Steven May.
Harrison Petty appears likely to swing back alongside Lever and Tom McDonald.
The Power dropped Dylan Williams for Jed McEntee.
Jack Macrae is among five inclusions on an extended bench for the Western Bulldogs' clash with West Coast on Sunday, along with Riley Garcia, James O'Donnell, Rory Lobb and Taylor Duryea.
The Bulldogs will make at least two changes with Ed Richards (concussion) and Nick Coffield (shoulder) sidelined.
Veteran Andrew Gaff is one of three additions to the Eagles' squad, alongside potential debutant Harvey Johnston and young key forward Jack Williams.
Important Richmond defender Nathan Broad has been named to return from calf soreness against Sydney on Sunday.
Tylar Young, who missed the Tigers' loss to Port Adelaide through concussion, and late withdrawal Maurice Rioli (back) are named on an extended bench alongside Tyler Sonsie and former Swan Sam Naismith.
James Tresize (ankle) and Judson Clarke (omitted) drop out.
Sydney are without Harry Cunningham (concussion), while Sam Wicks has been dropped.
Robbie Fox, Peter Ladhams, Jacob Konstanty, Caleb Mitchell and Aaron Francis are on the extended bench.
Fremantle have named an unchanged side to face Adelaide on Friday.
The Crows have dropped Sam Berry and lost Jordon Butts (ankle), while recalling James Borlase and Lachlan Sholl.
