Russia has launched a massive air attack on the capital Kyiv and other Ukrainian cities, injuring at least 18 people and damaging infrastructure facilities across the country, officials say.
Blasts were heard in Kyiv and the surrounding region on Thursday after an air raid alert, Reuters witnesses said.
Authorities reported sending rescue teams to several locations in the capital.
Interior Minister Ihor Klymenko said people were injured in Kyiv and Cherkasy regions and in the city of Kharkiv in the east during the attack that came early in the morning.
"It is a restless morning," he wrote on the Telegram messaging app.
"Explosions were heard in different regions of Ukraine."
Kyiv mayor Vitali Klitschko said seven people, including a nine-year girl, were injured in Kyiv.
Missile debris fell in the city centre and an infrastructure facility and several non-residential buildings were damaged, causing a fire, he said.
Klymenko said a hotel and several shopping kiosks were damaged in Cherkasy in central Ukraine and seven people were injured.
The emergency services posted a video on Telegram showing rescuers carrying out an injured man on a stretcher as a fire rages.
The interior ministry and regional officials reported blasts in Cherkasy, Kharkiv, Khmelnytskiy, Rivne, Vinnytsia, Lviv and Ivano-Frankivsk regions.
Maksym Kozytskyi, Lviv's regional governor, said three Russian missiles hit the city of Drohobych in the west, about 60km from the Polish border.
Kozytskiy said an infrastructure facility and warehouses were hit.
In a separate overnight attack, two people were killed by Russian shelling of a dormitory in the southern city of Kherson, governor Oleksandr Prokudin said.
Meanwhile, US President Joe Biden planned to announce a $US325 million ($A499 million) military aid package for Ukraine on Thursday to coincide with a visit to Washington DC by President Volodymyr Zelenskiy, a US official said on condition of anonymity.
The weapons aid package was expected to include the second tranche of cluster munitions fired by a 155mm Howitzer cannon, the US official said.
United Nations Special Rapporteur Alice Jill Edwards urged the US in a letter published on Wednesday to reconsider its decision to supply Ukraine with cluster munitions, saying these could harm civilians even decades after the end of the conflict there.
In her letter to the US government, Edwards said cluster munitions "indiscriminately and seriously injure civilians both at the time of use and in post-conflict" and should not be used.
"I respectfully urge Your Excellency's Government to reconsider the decision to transfer cluster munitions and to halt any plan towards the implementation of such decision," Edwards, the special rapporteur on torture and other cruel, inhuman or degrading treatment or punishment, wrote in the letter.
Cluster munitions are prohibited by more than 100 countries.
The weapons typically release large numbers of smaller bomblets that can kill indiscriminately across a wide area.
Those that fail to explode pose a danger long after a conflict ends.
In addition, the US plans to send more Avenger short-range air defence systems that use Stinger missiles, made by RTX Corp, formerly Raytheon, the official said.
The package is made possible by utilising Presidential Drawdown Authority, which authorises Biden to transfer articles and services from US stocks without congressional approval during an emergency.
The material will come from US excess inventory.
Zelenskiy is scheduled to visit Capitol Hill on Thursday morning to meet representatives before holding White House talks with Biden.
The US has sent more than $US40 billion ($A61 billion) worth of security assistance to Ukraine since the Russian invasion in February 2022.
